Description

[1-(5-Bromo-Pyridin-3-Yloxymethyl)-2-Methyl-Propyl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke compounds for client drug discovery programs.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in organic synthesis methodology and bioorganic chemistry.

Basic Information

Product Name	[1-(5-Bromo-Pyridin-3-Yloxymethyl)-2-Methyl-Propyl]-Carbamic Acid tert-Butyl Ester
CAS No.	882169-80-4
Molecular Formula	C15H21BrN2O3
Molecular Weight	357.25 g/mol
Synonyms	tert-Butyl N-[1-[(5-bromopyridin-3-yl)oxymethyl]-2-methylpropyl]carbamate; 1-[(5-Bromo-3-pyridinyloxy)methyl]-2-methylpropylcarbamic Acid 1,1-Dimethylethyl Ester; BOC-Protected Amino Pyridyl Ether Intermediate; (5-Bromo-pyridin-3-yloxymethyl)-isobutyl-carbamic Acid tert-Butyl Ester; N-BOC-1-[(5-Bromo-3-pyridyloxy)methyl]-2-methylpropylamine; 882169-80-4
EINECS	Contact for details

Quality Control

Our [1-(5-Bromo-Pyridin-3-Yloxymethyl)-2-Methyl-Propyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.