Description

tert-Butyl (2-((5-Bromopyridin-3-yl)oxy)ethyl)carbamate (Wx191459) is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine core protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce functionalized pyridine motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the bioactivity of the bromopyridine structure.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring precise bromination and protected amine chemistry.
• Academic Research: Used in university and institutional labs for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	tert-Butyl (2-((5-Bromopyridin-3-yl)oxy)ethyl)carbamate (Wx191459)
CAS No.	882169-78-0
Molecular Formula	C12H17BrN2O3
Molecular Weight	317.18 g/mol
Synonyms	Boc-2-((5-Bromo-3-pyridyl)oxy)ethylamine; 1,1-Dimethylethyl N-[2-[(5-bromo-3-pyridinyl)oxy]ethyl]carbamate; 2-((5-Bromopyridin-3-yl)oxy)ethan-1-amine, N-Boc protected; tert-Butyl N-[2-[(5-bromopyridin-3-yl)oxy]ethyl]carbamate; Wx191459; 5-Bromo-3-[(2-{[(tert-butoxy)carbonyl]amino}ethoxy)]pyridine; Carbamic acid, N-[2-[(5-bromo-3-pyridinyl)oxy]ethyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-((5-Bromopyridin-3-yl)oxy)ethyl)carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP (current Good Manufacturing Practice) applications where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.