Description

N4-(4-Methoxybenzyl)-2-Chloropyridine-3,4-Diamine is a high-purity, advanced pharmaceutical intermediate with the CAS number 881844-10-6. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular structure and reactivity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic amine structure.
• Chemical Synthesis: Serves as a versatile building block for constructing more complex heterocyclic compounds in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for method development and structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	N4-(4-Methoxybenzyl)-2-Chloropyridine-3,4-Diamine
CAS No.	881844-10-6
Molecular Formula	C13H14ClN3O
Molecular Weight	263.72 g/mol
Synonyms	2-Chloro-N4-(4-methoxybenzyl)pyridine-3,4-diamine; 2-Chloro-3,4-diamino-N-(4-methoxybenzyl)pyridine; 3,4-Diamino-2-chloro-N-(4-methoxybenzyl)pyridine; 881844-10-6; 4-Methoxybenzyl-2-chloropyridine-3,4-diamine; N-(4-Methoxybenzyl)-2-chloropyridine-3,4-diamine
EINECS	Contact for details

Quality Control

Our N4-(4-Methoxybenzyl)-2-Chloropyridine-3,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.