Description

8-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-2-Carbaldehyde is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity of the aldehyde group and the strategic halogen/fluorine substitution pattern, enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection, leveraging the trifluoromethyl group to enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, organic semiconductors, and photoactive compounds.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: A key substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	8-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-2-Carbaldehyde
CAS No.	881841-42-5
Molecular Formula	C9H4ClF3N2O
Molecular Weight	248.59 g/mol
Synonyms	8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxaldehyde; 2-Formyl-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine; 881841-42-5; Imidazo[1,2-a]pyridine-2-carbaldehyde, 8-chloro-6-(trifluoromethyl)-; 8-Chloro-6-trifluoromethyl-imidazo[1,2-a]pyridine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 8-Chloro-6-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-2-Carbaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), identity confirmation, and impurity profile is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.