Description

2-Chloro-4-(3,4-Difluorophenyl)Pyridine is a high-value, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its precise molecular architecture, which serves as a critical intermediate for the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific halogenated and fluorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the bioactivity of the difluorophenyl and chloropyridine groups.
• Material Science Research: Serves as a precursor for creating functionalized ligands and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Chloro-4-(3,4-Difluorophenyl)Pyridine
CAS No.	881419-16-5
Molecular Formula	C11H6ClF2N
Molecular Weight	225.62 g/mol
Synonyms	2-Chloro-4-(3,4-difluorophenyl)pyridine; 4-(3,4-Difluorophenyl)-2-chloropyridine; 2-Chloro-4-(3,4-difluorophenyl)pyridine; 881419-16-5; 2-Chloro-4-(3,4-difluorophenyl)pyridine; Pyridine, 2-chloro-4-(3,4-difluorophenyl)-; 3,4-Difluoro-2'-chloro-4-pyridinylbenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(3,4-Difluorophenyl)Pyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity requirements suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC, GC, and NMR is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.