Description

2-Chloro-4-(3-Fluoro-4-Methoxyphenyl)Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines halogen and ether substituents on an aromatic pyridine scaffold, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in medicinal chemistry programs targeting kinase inhibition and other biological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex aromatic systems.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	2-Chloro-4-(3-Fluoro-4-Methoxyphenyl)Pyridine
CAS No.	881419-13-2
Molecular Formula	C₁₂H₉ClFNO
Molecular Weight	237.66 g/mol
Synonyms	2-Chloro-4-(3-fluoro-4-methoxyphenyl)pyridine; 4-(3-Fluoro-4-methoxyphenyl)-2-chloropyridine; 2-Chloro-4-(3-fluoro-4-methoxyphenyl)pyridine; Pyridine, 2-chloro-4-(3-fluoro-4-methoxyphenyl)-; 881419-13-2; 2-Chloro-4-(3-Fluoro-4-Methoxyphenyl)Pyridine; 2-Chloro-4-(3-Fluoro-4-Methoxy-Phenyl)Pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Fluoro-4-Methoxyphenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.