Description

Benzoic Acid, 2-Bromo-3-Fluoro-5-Nitro-, Methyl Ester is a high-purity, multi-functional aromatic ester derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical and agrochemical research, offering unique reactivity due to its strategically positioned bromo, fluoro, and nitro substituents. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in developing new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with tailored electronic properties.
• Organic Synthesis: An essential reagent for Suzuki-Miyaura and other cross-coupling reactions, facilitated by the reactive bromo substituent.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays due to its distinct spectroscopic signature.
• Dye & Pigment Intermediate: Used in the synthesis of complex, nitro-containing dyes and colorants.

Basic Information

Product Name	Benzoic Acid, 2-Bromo-3-Fluoro-5-Nitro-, Methyl Ester
CAS No.	881415-30-1
Molecular Formula	C8H5BrFNO4
Molecular Weight	278.03 g/mol
Synonyms	Methyl 2-Bromo-3-fluoro-5-nitrobenzoate; 2-Bromo-3-fluoro-5-nitrobenzoic Acid Methyl Ester; Benzoic acid, 2-bromo-3-fluoro-5-nitro-, methyl ester; Methyl 2-bromo-3-fluoro-5-nitrobenzoate; 881415-30-1; Methyl 3-fluoro-2-bromo-5-nitrobenzoate; 2-Bromo-3-fluoro-5-nitro-methylbenzoate
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Bromo-3-Fluoro-5-Nitro-, Methyl Ester is manufactured under ISO 9001 quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.