Description

2-(4-Bromophenyl)-6-Chloropyridine-4-Carbaldehyde is a versatile and high-purity organic building block used in advanced chemical synthesis. This compound is valued for its unique halogenated pyridine-carbaldehyde structure, which makes it a critical intermediate for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic system.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: The bromophenyl moiety makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Library Development: Used in high-throughput screening and combinatorial chemistry to generate diverse compound libraries for drug discovery.

Basic Information

Product Name	2-(4-Bromophenyl)-6-Chloropyridine-4-Carbaldehyde
CAS No.	881402-41-1
Molecular Formula	C12H7BrClNO
Molecular Weight	296.55 g/mol
Synonyms	6-Chloro-2-(4-bromophenyl)pyridine-4-carboxaldehyde; 4-Bromo-2-(6-chloropyridin-2-yl)benzaldehyde; 2-(4-Bromophenyl)-6-chloro-4-pyridinecarboxaldehyde; 6-Chloro-2-(p-bromophenyl)isonicotinaldehyde; (6-Chloro-2-(4-bromophenyl)pyridin-4-yl)methanal; 4-Formyl-6-chloro-2-(4-bromophenyl)pyridine; 881402-41-1
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-6-Chloropyridine-4-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most sensitive R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.