Description

Hexahydro-2-[(3-Methyl-4-Pyridinyl)Methyl]-1H-Azepine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily required by research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and the production of specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in neurological and psychiatric research.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex nitrogen-containing heterocycles.
• Process Chemistry: Serves as a critical starting material or intermediate in scale-up and optimization of API manufacturing processes.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor ligands for biological studies.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals with specific biological activity.

Basic Information

Product Name	Hexahydro-2-[(3-Methyl-4-Pyridinyl)Methyl]-1H-Azepine
CAS No.	881040-70-6
Molecular Formula	C12H20N2
Molecular Weight	192.30 g/mol
Synonyms	2-[(3-Methyl-4-pyridinyl)methyl]hexahydro-1H-azepine; 1H-Azepine, hexahydro-2-[(3-methyl-4-pyridinyl)methyl]-; Hexahydro-2-[(3-methylpyridin-4-yl)methyl]-1H-azepine; 4-[(Hexahydro-1H-azepin-2-yl)methyl]-3-methylpyridine; 3-Methyl-4-(azepan-2-ylmethyl)pyridine; Azepane derivative CAS 881040-70-6; Advanced Pharmaceutical Intermediate 881040-70-6
EINECS	Contact for details

Quality Control

Our Hexahydro-2-[(3-Methyl-4-Pyridinyl)Methyl]-1H-Azepine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.