Description

5-Bromo-2-Fluoro-3-Methoxypyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists developing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Used in the research and production of specialty polymers, liquid crystals, and electronic materials.
• Chemical Research: Versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	5-Bromo-2-Fluoro-3-Methoxypyridine
CAS No.	880870-66-6
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	3-Methoxy-5-bromo-2-fluoropyridine; 2-Fluoro-3-methoxy-5-bromopyridine; 5-Bromo-2-fluoro-3-methoxypyridine; 880870-66-6; Pyridine, 5-bromo-2-fluoro-3-methoxy-; 5-Br-2-F-3-MeO-Pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-3-Methoxypyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.