Description

1-(3,5-Dichloro-2-Methoxyphenyl)-n-(Pyridin-4-Ylmethyl)Methanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining substituted phenyl and pyridinylmethylamine moieties. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel bioactive molecules targeting central nervous system and inflammatory pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in neuroscience and immunology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile chemical structure.
• Active Pharmaceutical Ingredient (API) Development: A precursor in multi-step synthetic routes for potential APIs targeting G-protein-coupled receptors (GPCRs).
• Biochemical Probe Synthesis: Employed in creating specialized probes and tool compounds for biological target validation and assay development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Used in university and institutional laboratories for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	1-(3,5-Dichloro-2-Methoxyphenyl)-n-(Pyridin-4-Ylmethyl)Methanamine
CAS No.	880809-46-1
Molecular Formula	C14H14Cl2N2O
Molecular Weight	297.18 g/mol
Synonyms	1-(3,5-Dichloro-2-methoxyphenyl)-N-(pyridin-4-ylmethyl)methanamine; N-[(3,5-Dichloro-2-methoxyphenyl)methyl]-4-pyridinemethanamine; Methanamine, 1-(3,5-dichloro-2-methoxyphenyl)-N-(4-pyridinylmethyl)-; 4-({[(3,5-Dichloro-2-methoxyphenyl)methyl]amino}methyl)pyridine; 880809-46-1
EINECS	Contact for details

Quality Control

Our 1-(3,5-Dichloro-2-Methoxyphenyl)-n-(Pyridin-4-Ylmethyl)Methanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for advanced pharmaceutical intermediate applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.