Description

2(1H)-Isoquinolinecarboxylic Acid, 1-[(4-Amino-3-Iodophenyl)Methyl]-6,7-Bis[(Ethoxycarbonyl)Oxy]-3,4-Dihydro-, 9H-Fluoren-9-Ylmethyl Ester is a sophisticated, multi-functional chemical building block designed for advanced synthetic applications. This compound is valued for its complex molecular architecture, which incorporates protected functional groups ideal for selective deprotection and further derivatization in multi-step organic syntheses. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its unique isoquinoline and fluorenylmethyl ester structure.
• Peptide Mimetics & PROTACs: Acts as a versatile scaffold for constructing peptide mimetics and Proteolysis-Targeting Chimeras (PROTACs) due to its modifiable functional handles.
• Fluorescent Probe Synthesis: The fluorenylmethyl (Fm) protecting group and aromatic structure make it suitable for creating specialized fluorescent tags and molecular probes.
• Material Science Research: Investigated as a monomer or additive for creating advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	2(1H)-Isoquinolinecarboxylic Acid, 1-[(4-Amino-3-Iodophenyl)Methyl]-6,7-Bis[(Ethoxycarbonyl)Oxy]-3,4-Dihydro-, 9H-Fluoren-9-Ylmethyl Ester
CAS No.	880475-02-5
Molecular Formula	C37H33IN2O8
Molecular Weight	784.57 g/mol
Synonyms	9H-Fluoren-9-ylmethyl 1-[(4-amino-3-iodophenyl)methyl]-6,7-bis(ethoxycarbonyloxy)-3,4-dihydroisoquinoline-2(1H)-carboxylate; Fmoc-Protected Amino-Isoquinoline Derivative; 1-[(4-Amino-3-iodobenzyl)]-6,7-di(ethoxycarbonyloxy)-3,4-dihydro-2(1H)-isoquinolinecarboxylic Acid 9-Fluorenylmethyl Ester; CAS 880475-02-5; 880475-02-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While typically supplied as a high-purity research grade, we can discuss custom synthesis under GMP-like conditions for pre-clinical and clinical trial material needs, with documentation tailored to meet regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep the container tightly sealed in a desiccator to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.