Description

2-Pyridin-4-Yl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine CAS NO 880361-85-3 is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. Its complex, nitrogen-rich bicyclic structure makes it a critical building block for medicinal chemistry research and development. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Used in research for creating novel kinase inhibitors due to its pyrimidine core, which is common in many targeted cancer therapies.
• Medicinal Chemistry Research: Employed as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Chemical Biology Probes: Utilized in the development of chemical probes to study specific biological processes and protein functions.
• Custom Synthesis: Provided for contract research organizations (CROs) and pharmaceutical companies requiring bespoke intermediates for proprietary synthesis routes.
• Academic Research: Supplied to universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Pyridin-4-Yl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine
CAS No.	880361-85-3
Molecular Formula	C15H14N4
Molecular Weight	250.30 g/mol
Synonyms	2-(Pyridin-4-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 4-(5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidin-2-yl)pyridine; Pyrido[4,3-d]pyrimidine, 2-(4-pyridinyl)-5,6,7,8-tetrahydro-; 880361-85-3; 2-(4-Pyridyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 2-Pyridin-4-yl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Every batch of our 2-Pyridin-4-Yl-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidine is manufactured under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency essential for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.