Description

Pyrido[4,3-D]Pyrimidine, 5,6,7,8-Tetrahydro-2-(2-Pyridinyl)- is a high-purity, heterocyclic organic compound with the CAS number 880361-82-0, serving as a critical advanced pharmaceutical intermediate and key building block in medicinal chemistry. Its fused pyrido-pyrimidine core structure makes it a valuable scaffold for the research and development of novel therapeutic agents. This compound is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers focused on kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic assays and target validation studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value heterocyclic compounds for specialized applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in university and institutional labs for fundamental research in organic chemistry and pharmacology.

Basic Information

Product Name	Pyrido[4,3-D]Pyrimidine, 5,6,7,8-Tetrahydro-2-(2-Pyridinyl)-
CAS No.	880361-82-0
Molecular Formula	C12H12N4
Molecular Weight	212.25 g/mol
Synonyms	2-(Pyridin-2-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 5,6,7,8-Tetrahydro-2-(2-pyridinyl)pyrido[4,3-d]pyrimidine; 2-(2-Pyridinyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; Pyrido[4,3-d]pyrimidine, 5,6,7,8-tetrahydro-2-(2-pyridinyl)-; 880361-82-0; Tetrahydro-2-(2-pyridinyl)pyrido[4,3-d]pyrimidine; SCHEMBL18883027; AOB81117
EINECS	Contact for details

Quality Control

Our Pyrido[4,3-D]Pyrimidine, 5,6,7,8-Tetrahydro-2-(2-Pyridinyl)- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades Available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.