Description

3-Pyridinemethanol, 5-Butyl-4-(4-Fluoro-2-Hydroxyphenyl)-A-Methyl-2,6-Bis(1-Methylethyl)-, (Ar)- is a complex, multi-functional pyridine derivative designed for advanced synthetic applications. This compound matters as a sophisticated chiral building block, offering a unique molecular scaffold with a fluorinated phenolic moiety and sterically hindered isopropyl groups, which are critical for modulating biological activity and material properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the fluorinated aromatic system can enhance bioavailability and environmental stability.
• Ligand Synthesis: Acts as a starting material for creating complex, polydentate ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated as a monomer or additive for specialty polymers, where its structure can impart specific optical or electronic properties.
• Chemical Biology: Employed as a molecular probe to study enzyme interactions and biological pathways due to its tailored structural features.

Basic Information

Product Name	3-Pyridinemethanol, 5-Butyl-4-(4-Fluoro-2-Hydroxyphenyl)-A-Methyl-2,6-Bis(1-Methylethyl)-, (Ar)-
CAS No.	880343-35-1
Molecular Formula	C23H32FNO2
Molecular Weight	373.51 g/mol
Synonyms	(αR)-5-Butyl-α-methyl-2,6-bis(1-methylethyl)-4-[4-fluoro-2-hydroxyphenyl]-3-pyridinemethanol; (R)-5-Butyl-4-(4-fluoro-2-hydroxyphenyl)-α-methyl-2,6-diisopropyl-3-pyridinemethanol; 5-Butyl-4-(4-fluoro-2-hydroxyphenyl)-α-methyl-2,6-diisopropyl-3-pyridinemethanol (R-isomer); AR-880343-35-1; CAS 880343-35-1
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management under an ISO-certified system. Every batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure reproducible performance in your synthetic workflows. A detailed Certificate of Analysis (COA) providing identity, purity (HPLC), and chiral excess data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.