Description

4-(6-Chloropyridine-3-Ylethynyl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique conjugated alkyne-linked aromatic structure. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and materials science research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products.
• Material Science: Serves as a precursor for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), due to its extended π-conjugation.
• Chemical Biology: Employed as a molecular probe or linker in bioconjugation and proteomics research.
• Academic & Industrial R&D: Fundamental reagent for methodological development in synthetic organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	4-(6-Chloropyridine-3-Ylethynyl)Benzonitrile
CAS No.	880266-35-3
Molecular Formula	C14H7ClN2
Molecular Weight	238.67 g/mol
Synonyms	4-[(6-Chloro-3-pyridinyl)ethynyl]benzonitrile; 4-((6-Chloropyridin-3-yl)ethynyl)benzonitrile; Benzonitrile, 4-[(6-chloro-3-pyridinyl)ethynyl]-; 880266-35-3; 4-(6-Chloro-pyridin-3-ylethynyl)-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-(6-Chloropyridine-3-Ylethynyl)Benzonitrile is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports cGMP and ISO standards for reliable integration into regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.