Description

4-(5-Bromopyridine-2-Ylethynyl)Benzonitrile is a specialized organic building block featuring a bromopyridine core linked to a benzonitrile moiety via an ethynyl bridge. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of organic semiconductors, conductive polymers, and liquid crystals.
• Chemical Biology Probe: Utilized in the design of molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(5-Bromopyridine-2-Ylethynyl)Benzonitrile
CAS No.	880266-33-1
Molecular Formula	C14H7BrN2
Molecular Weight	283.13 g/mol
Synonyms	4-[(5-Bromo-2-pyridinyl)ethynyl]benzonitrile; 2-[(4-Cyanophenyl)ethynyl]-5-bromopyridine; 5-Bromo-2-[(4-cyanophenyl)ethynyl]pyridine; 4-(5-Bromopyridin-2-ylethynyl)benzonitrile; Benzonitrile, 4-[(5-bromo-2-pyridinyl)ethynyl]-; 880266-33-1
EINECS	Contact for details

Quality Control

Our 4-(5-Bromopyridine-2-Ylethynyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.