Description

Cyclobutanecarboxylic Acid, 1-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester is a high-purity, protected amino acid derivative featuring a cyclobutane ring, a key structural motif in advanced organic synthesis. This compound is valued for its role as a sophisticated building block in the development of novel pharmaceuticals and bioactive molecules, enabling precise control over molecular architecture. It is primarily sought by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing stability and biological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Synthesis: Potential intermediate for creating novel herbicides or fungicides with unique modes of action.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, Methyl Ester
CAS No.	880166-10-9
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)amino]cyclobutanecarboxylic acid methyl ester; Methyl 1-[(tert-butoxycarbonyl)amino]cyclobutanecarboxylate; Boc-1-Aminocyclobutanecarboxylic Acid Methyl Ester; Methyl 1-(Boc-amino)cyclobutanecarboxylate; 1-(Boc-amino)cyclobutanecarboxylic acid methyl ester; 1-N-Boc-aminocyclobutanecarboxylic Acid Methyl Ester; (1-((tert-Butoxycarbonyl)amino)cyclobutyl)formic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.