Description

(2-Oxo-2',3',5',6'-Tetrahydrospiro[Indole-3,4'-Pyran]-2(1H)-Yl)Acetic Acid CAS NO 880079-26-5 is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic indole-pyran structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• CNS Drug Development: Serves as a core scaffold for compounds being investigated for neurological and psychiatric disorders.
• Anti-inflammatory Agent Synthesis: Employed in the research and production of potential anti-inflammatory medications.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and protein interactions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	(2-Oxo-2',3',5',6'-Tetrahydrospiro[Indole-3,4'-Pyran]-2(1H)-Yl)Acetic Acid
CAS No.	880079-26-5
Molecular Formula	C15H15NO4
Molecular Weight	273.28 g/mol
Synonyms	Spiro[indole-3,4'-pyran]-2(1H)-acetic acid, 2-oxo-2',3',5',6'-tetrahydro-; 2-(2-Oxo-2',3',5',6'-tetrahydrospiro[1H-indole-3,4'-pyran]-1-yl)acetic acid; 880079-26-5; Spiro[indole-pyran] acetic acid derivative; (2-Oxo-2,3,5,6-tetrahydrospiro[indole-3,4-pyran]-1-yl)acetic acid; 1-(Carboxymethyl)-2-oxo-2,3,5,6-tetrahydrospiro[indole-3,4'-pyran]; Spirocyclic indole acetic acid.
EINECS	Contact for details

Quality Control

Our (2-Oxo-2',3',5',6'-Tetrahydrospiro[Indole-3,4'-Pyran]-2(1H)-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.