Description

1-(4-Isocyanatophenyl)-4-Methylpiperazine is a specialized aromatic isocyanate derivative that serves as a high-value building block in advanced organic synthesis. This compound is critical for introducing reactive isocyanate functionality into complex molecular architectures, enabling the creation of novel polymers and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical and advanced materials sectors for applications in drug discovery and the development of high-performance polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Polymer Chemistry: Used as a monomer or cross-linking agent in the production of specialty polyurethanes, polyureas, and other high-performance polymers with tailored thermal and mechanical properties.
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Utilized in academic and industrial R&D for creating novel coatings, adhesives, and functional materials with specific surface properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences and specialty chemicals markets.

Basic Information

Product Name	1-(4-Isocyanatophenyl)-4-Methylpiperazine
CAS No.	879896-39-6
Molecular Formula	C12H15N3O
Molecular Weight	217.27 g/mol
Synonyms	4-Isocyanato-1-(4-methylpiperazin-1-yl)benzene; 1-(4-Methylpiperazin-1-yl)-4-isocyanatobenzene; 4-(4-Methylpiperazin-1-yl)phenyl isocyanate; p-(N-Methylpiperazino)phenyl isocyanate; 4-Isocyanatophenyl-4-methylpiperazine; N-Methyl-N'-(4-isocyanatophenyl)piperazine
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Isocyanatophenyl)-4-Methylpiperazine undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), identity confirmation, and impurity profiles is provided with each shipment to guarantee reliable and reproducible performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.