Description

2-(6-Bromo-3-Pyridyl)-1,1,1-Trifluoro-2-Propanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a bromo-substituted pyridine ring and a trifluoromethyl carbinol group, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used to develop new generations of herbicides, insecticides, and fungicides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Building block for creating fluorinated polymers and advanced organic electronic materials with enhanced stability and performance.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	2-(6-Bromo-3-Pyridyl)-1,1,1-Trifluoro-2-Propanol
CAS No.	879487-92-0
Molecular Formula	C8H6BrF3NO
Molecular Weight	269.04 g/mol
Synonyms	6-Bromo-3-(1,1,1-trifluoro-2-hydroxypropyl)pyridine; 1,1,1-Trifluoro-2-(6-bromopyridin-3-yl)propan-2-ol; 2-Propanol, 1,1,1-trifluoro-2-(6-bromo-3-pyridinyl)-; 2-(6-Bromo-3-pyridinyl)-1,1,1-trifluoro-2-propanol; α-(Trifluoromethyl)-6-bromonicotinemethanol
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-3-Pyridyl)-1,1,1-Trifluoro-2-Propanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ISO 9001 standards guarantee a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.