Description

(S)-n-Boc-2-Aminomethylmorpholine CAS NO 879403-42-6 is a high-purity, chiral building block and protected amine derivative essential for advanced organic synthesis. Its primary value lies in providing a stereochemically defined scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is critically needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Peptidomimetic Chemistry: Used to introduce constrained morpholine and amine functionalities into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complexation.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereospecific pesticides and herbicides.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs serving the life sciences sector.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-n-Boc-2-Aminomethylmorpholine
CAS No.	879403-42-6
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	(S)-tert-Butyl 2-(aminomethyl)morpholine-4-carboxylate; (S)-4-(tert-Butoxycarbonyl)-2-aminomethylmorpholine; (S)-N-Boc-2-Aminomethylmorpholine; (S)-2-(Aminomethyl)-N-Boc-morpholine; (S)-Boc-Ammor; (S)-2-(Boc-amino-methyl)morpholine; (2S)-2-[(tert-Butoxycarbonylamino)methyl]morpholine; (S)-2-((tert-Butoxycarbonylamino)methyl)morpholine
EINECS	Contact for details

Quality Control

Our (S)-n-Boc-2-Aminomethylmorpholine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade materials for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.