Description

Cyclopropanecarboxylic Acid, 2-(4-Fluorophenyl)-, Ethyl Ester is a high-purity fluorinated cyclopropane derivative, a crucial building block in modern pharmaceutical and agrochemical synthesis. Its value lies in the unique three-membered cyclopropane ring and the strategically placed fluorine atom, which are essential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This advanced intermediate is primarily sought after by R&D chemists and process development scientists in the pharmaceutical industry for the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in therapeutic areas such as CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane moiety can enhance potency and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(4-Fluorophenyl)-, Ethyl Ester
CAS No.	879324-63-7
Molecular Formula	C12H13FO2
Molecular Weight	208.23 g/mol
Synonyms	Ethyl 2-(4-fluorophenyl)cyclopropanecarboxylate; 2-(4-Fluorophenyl)cyclopropanecarboxylic Acid Ethyl Ester; 4-Fluorophenylcyclopropanecarboxylic Acid Ethyl Ester; 1-(4-Fluorophenyl)cyclopropanecarboxylic Acid Ethyl Ester (regioisomer); F-CPCE; 879324-63-7; Ethyl (2-(4-fluorophenyl)cyclopropyl)carboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(4-Fluorophenyl)-, Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.