Description

4-Carboxy-Pennsylvania Green CAS NO 879288-14-9 is a chemically modified, water-soluble derivative of the Pennsylvania Green fluorophore, designed to expand its utility in advanced labeling applications. This compound is critical for researchers and developers requiring a reactive, carboxylic acid-functionalized probe for covalent conjugation to biomolecules. It is primarily needed by professionals in the life sciences, analytical chemistry, and diagnostic reagent manufacturing sectors for creating sensitive detection assays.

Application

• Fluorescent Labeling Reagent: Used as an active ester (e.g., NHS ester) for covalently tagging proteins, antibodies, peptides, and nucleic acids to impart fluorescence.
• Bioconjugation & Probe Synthesis: Serves as a key intermediate in the synthesis of custom fluorescent probes and biosensors for research and diagnostic applications.
• Cell & Tissue Staining: Employed in the development of fluorescent dyes for imaging applications in microscopy (e.g., confocal, fluorescence).
• Flow Cytometry: Used to create antibody-dye conjugates for multiparameter analysis in immunophenotyping and cell sorting.
• Diagnostic Assay Development: Integral for manufacturing components of ELISA kits, lateral flow assays, and other in vitro diagnostic (IVD) products.
• Material Science: Applied in the surface functionalization of nanoparticles and polymers for traceable material studies.

Basic Information

Product Name	4-Carboxy-Pennsylvania Green
CAS No.	879288-14-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pennsylvania Green carboxylic acid; 4-Carboxy-PG; PG-COOH; Carboxy-functionalized Pennsylvania Green; Fluorescent tracer acid derivative; 2,7-Dichloro-3,6-dihydroxy-9H-xanthene-9-one-4-carboxylic acid (related core structure); Reactive Pennsylvania Green dye
EINECS	Contact for details

Quality Control

Our 4-Carboxy-Pennsylvania Green is produced under a rigorous quality management system. Each batch is characterized and tested to ensure high purity and consistent performance for sensitive bioconjugation work. Certificates of Analysis (COA) detailing purity (by HPLC), identity confirmation, and other critical parameters are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive; prolonged exposure to light should be avoided to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Absorption Max (λmax)	Contact for details
Emission Max (λem)	Contact for details
Extinction Coefficient	Contact for details
Water Content (KF)	< 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.