Description

3,3-Dibromo-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One is a high-value, multi-functional synthetic intermediate designed for advanced pharmaceutical and agrochemical research. This compound is critical for constructing complex heterocyclic scaffolds, enabling the development of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology: Serves as a versatile probe or precursor in the study of biological pathways and target identification.
• Material Science: Potential precursor for specialized organic electronic materials or ligands in catalysis.
• Process Chemistry: Enables scalable routes to complex molecules in pilot plant and commercial manufacturing.
• Contract Research & Development (CRO/CMO): Essential reagent for custom synthesis and library generation services.

Basic Information

Product Name	3,3-Dibromo-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One
CAS No.	879132-47-5
Molecular Formula	C14H20Br2N2O2Si
Molecular Weight	452.22 g/mol
Synonyms	3,3-Dibromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 3,3-Dibromo-1-((2-(trimethylsilyl)ethoxy)methyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-one; 879132-47-5; 1H-Pyrrolo[2,3-b]pyridin-2(3H)-one, 3,3-dibromo-1-[(2-(trimethylsilyl)ethoxy)methyl]-; SEM-protected 3,3-dibromo-7-azaindolin-2-one
EINECS	Contact for details

Quality Control

Our 3,3-Dibromo-1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.