Description

Allothreonine, n-Acetyl-, Ethyl Ester Of Dl- (5Ci) is a specialized, high-purity chemical building block used in advanced organic synthesis. This compound matters for its role as a protected amino acid derivative, enabling precise and efficient construction of complex peptide and peptidomimetic structures. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in peptide-based drug discovery.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and the synthesis of complex molecular libraries for high-throughput screening.
• Biochemical Research: Serves as a precursor or substrate in enzymatic studies and the investigation of metabolic pathways.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified threonine residues.
• Proteomics & Chemical Biology: Utilized as a tool compound for labeling, cross-linking, or probing protein structure and function.
• Academic Research: Fundamental studies in organic synthesis methodology and stereochemistry.

Basic Information

Product Name	Allothreonine, n-Acetyl-, Ethyl Ester Of Dl- (5Ci)
CAS No.	879124-16-0
Molecular Formula	C9H17NO5
Molecular Weight	219.24 g/mol
Synonyms	DL-Allothreonine, N-Acetyl-, ethyl ester; Ethyl N-acetyl-DL-allothreoninate; N-Acetyl-DL-allothreonine ethyl ester; Ac-DL-aThr-OEt; 2-Acetamido-3-hydroxybutanoic acid ethyl ester (alloisomer); Ethyl 2-acetamido-3-hydroxybutanoate (alloisomer); (2R*,3S*)-Ethyl 2-acetamido-3-hydroxybutanoate; (2R,3S)- and (2S,3R)-Ethyl 2-acetamido-3-hydroxybutanoate
EINECS	Contact for details

Quality Control

Our Allothreonine, n-Acetyl-, Ethyl Ester Of Dl- (5Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized by modern analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.