Description

3-Acetylpicolinonitrile is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive acetyl and nitrile functional groups. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects requiring complex heterocyclic chemistry.
• Academic and Industrial R&D: Used in exploratory chemistry for discovering new chemical entities and reaction pathways.

Basic Information

Product Name	3-Acetylpicolinonitrile
CAS No.	879093-49-9
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	1-(3-Cyanopyridin-2-yl)ethanone; 2-Acetyl-3-cyanopyridine; 3-Cyano-2-acetylpyridine; 3-Acetyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 3-acetyl-; 3-Acetylpyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Acetylpicolinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by HPLC, GC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.