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tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate CAS NO 878905-11-4
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CAS No.:878905-11-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block for the development of complex molecules, offering a reactive handle for further functionalization via its sulfonyloxy group. It is primarily utilized by researchers and process chemists in the pharmaceutical and biotechnology sectors for the synthesis of peptide mimetics, active pharmaceutical ingredients (APIs), and other bioactive compounds.
Application
- Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
- Peptidomimetic Synthesis: Used to construct non-natural amino acid residues and peptide backbones for drug discovery programs.
- Chemical Biology Probe Development: Serves as a precursor for labeling reagents and molecular probes used in biochemical research.
- Custom Synthesis & Contract Manufacturing: An essential raw material for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds.
- Academic Research: Employed in university and institutional labs for methodological development in organic and medicinal chemistry.
Basic Information
| Product Name | tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate |
| CAS No. | 878905-11-4 |
| Molecular Formula | C16H31NO7S |
| Molecular Weight | 381.49 g/mol |
| Synonyms | Boc-6-(Methylsulfonyloxy)-L-norleucine tert-Butyl Ester; 6-(Methylsulfonyloxy)-N-Boc-L-norleucine tert-Butyl Ester; tert-Butyl (2S)-2-[(tert-butoxy)carbonylamino]-6-(methylsulfonyloxy)hexanoate; N-α-Boc-6-O-mesyl-L-homoserine tert-Butyl Ester; Boc-Hse(OMs)-OtBu; (2S)-2-[(tert-Butoxycarbonyl)amino]-6-[(methylsulfonyl)oxy]hexanoic acid tert-butyl ester; Amino Acid Derivative 878905-11-4 |
| EINECS | Contact for details |
Quality Control
Our production of tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥97.0% |
| Purity (HPLC, Area %) | ≥98.0% |
| Optical Rotation | Contact for details |
| Water Content (KF) | ≤0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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