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tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate CAS NO 878905-11-4


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CAS No.:878905-11-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate is a high-purity, protected amino acid derivative designed for advanced organic synthesis. This compound is a critical building block for the development of complex molecules, offering a reactive handle for further functionalization via its sulfonyloxy group. It is primarily utilized by researchers and process chemists in the pharmaceutical and biotechnology sectors for the synthesis of peptide mimetics, active pharmaceutical ingredients (APIs), and other bioactive compounds.

Application

  • Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
  • Peptidomimetic Synthesis: Used to construct non-natural amino acid residues and peptide backbones for drug discovery programs.
  • Chemical Biology Probe Development: Serves as a precursor for labeling reagents and molecular probes used in biochemical research.
  • Custom Synthesis & Contract Manufacturing: An essential raw material for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds.
  • Academic Research: Employed in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate
CAS No. 878905-11-4
Molecular Formula C16H31NO7S
Molecular Weight 381.49 g/mol
Synonyms Boc-6-(Methylsulfonyloxy)-L-norleucine tert-Butyl Ester; 6-(Methylsulfonyloxy)-N-Boc-L-norleucine tert-Butyl Ester; tert-Butyl (2S)-2-[(tert-butoxy)carbonylamino]-6-(methylsulfonyloxy)hexanoate; N-α-Boc-6-O-mesyl-L-homoserine tert-Butyl Ester; Boc-Hse(OMs)-OtBu; (2S)-2-[(tert-Butoxycarbonyl)amino]-6-[(methylsulfonyl)oxy]hexanoic acid tert-butyl ester; Amino Acid Derivative 878905-11-4
EINECS Contact for details

Quality Control

Our production of tert-Butyl 2-(tert-Butoxycarbonylamino)-6-(Methylsulfonyloxy)Hexanoate adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥97.0%
Purity (HPLC, Area %) ≥98.0%
Optical Rotation Contact for details
Water Content (KF) ≤0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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