Description

5-Bromo-2-(4-Boc-Piperazin-1-Yl)-3-Methylpyridine is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core linked to a Boc-protected piperazine moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on oncology, CNS, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and target validation.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of proprietary compounds and advanced intermediates.
• Academic Research: Utilized in university and institutional labs for novel synthetic methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	5-Bromo-2-(4-Boc-Piperazin-1-Yl)-3-Methylpyridine
CAS No.	878809-70-2
Molecular Formula	C16H24BrN3O2
Molecular Weight	370.29 g/mol
Synonyms	1-Boc-4-(5-Bromo-3-methyl-2-pyridyl)piperazine; tert-Butyl 4-(5-bromo-3-methylpyridin-2-yl)piperazine-1-carboxylate; 5-Bromo-3-methyl-2-(1-piperazinyl)pyridine 1-Boc derivative; 5-Bromo-2-(1-Boc-4-piperazinyl)-3-methylpyridine; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-5-bromo-3-methylpyridine; 878809-70-2; 5-Bromo-2-(N-Boc-piperazin-1-yl)-3-methylpyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(4-Boc-Piperazin-1-Yl)-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.