Description

5-Piperidin-1-Ylnicotinic Acid CAS NO 878742-33-7 is a high-purity organic compound belonging to the nicotinic acid derivative class, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This product is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound discovery.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to introduce the piperidine-nicotinic acid pharmacophore.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic & Institutional Research: Employed in university and institutional laboratories for pioneering research in organic synthesis and drug discovery.

Basic Information

Product Name	5-Piperidin-1-Ylnicotinic Acid
CAS No.	878742-33-7
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	5-(Piperidin-1-yl)nicotinic acid; 5-(1-Piperidinyl)-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 5-(1-piperidinyl)-; Nicotinic acid, 5-piperidino-; 5-Piperidin-1-yl-pyridine-3-carboxylic acid; 5-(Piperidin-1-yl)pyridine-3-carboxylic acid; 878742-33-7 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Piperidin-1-Ylnicotinic Acid is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines and can support development projects requiring material for pre-clinical and clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.