Description

o-(2-Azido-4,6-o-Benzylidene-2-Deoxy-α-D-Galactopyranosyl)-n-Fmoc-L-Serine tert-Butyl Ester is a sophisticated, multi-functional building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring high-purity intermediates for complex carbohydrate and glycoconjugate synthesis. It is primarily utilized in pharmaceutical R&D, particularly in the development of novel therapeutics, vaccines, and diagnostic agents where precise glycosylation is essential.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex oligosaccharides and glycopeptides for drug discovery programs.
• Glycoconjugate Synthesis: Used in the preparation of carbohydrate-based antigens and vaccine candidates.
• Chemical Biology Tool: Enables site-specific labeling and conjugation studies of biomolecules via its azide and Fmoc-protected functional groups.
• Peptide & Carbohydrate Chemistry: Serves as a protected serine glycoside derivative for solid-phase peptide synthesis (SPPS) and solution-phase coupling reactions.
• Academic & Industrial Research: Essential for investigating glycosylation pathways, enzyme mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	o-(2-Azido-4,6-o-Benzylidene-2-Deoxy-α-D-Galactopyranosyl)-n-Fmoc-L-Serine tert-Butyl Ester
CAS No.	878483-02-4
Molecular Formula	C39H44N4O9
Molecular Weight	712.80 g/mol
Synonyms	Fmoc-Ser[Gal(OBn, N3)]-OtBu; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[2-azido-4,6-O-benzylidene-2-deoxy-α-D-galactopyranosyl]-L-serine 1,1-dimethylethyl ester; tert-Butyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-[2-azido-4,6-O-(phenylmethylene)-2-deoxy-α-D-galactopyranosyl]-L-serinate; Fmoc-L-Serine, O-[2-azido-4,6-O-benzylidene-2-deoxy-α-D-galactopyranosyl]-, 1,1-dimethylethyl ester; Glycosylated Fmoc-Serine-OtBu derivative; Azido-galactose serine building block; 878483-02-4
EINECS	Contact for details

Quality Control

Our o-(2-Azido-4,6-o-Benzylidene-2-Deoxy-α-D-Galactopyranosyl)-n-Fmoc-L-Serine tert-Butyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is moisture-sensitive; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.