Description

2-(Chloromethyl)-5-Fluoroimidazo[1,2-A]Pyridine is a high-value pharmaceutical intermediate and versatile chemical building block. This compound is critical for the synthesis of complex molecules, offering a reactive chloromethyl group and a fluorinated heterocyclic core for targeted modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients. Its precise structure enables the creation of compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require fluorinated heterocyclic scaffolds.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via nucleophilic substitution reactions at the chloromethyl site.
• Material Science: Potential intermediate for creating specialty polymers or organic electronic materials with unique properties.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and industrial R&D labs.

Basic Information

Product Name	2-(Chloromethyl)-5-Fluoroimidazo[1,2-A]Pyridine
CAS No.	878198-71-1
Molecular Formula	C8H6ClFN2
Molecular Weight	184.60 g/mol
Synonyms	5-Fluoro-2-(chloromethyl)imidazo[1,2-a]pyridine; 2-(Chloromethyl)-5-fluoroimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-(chloromethyl)-5-fluoro-; 878198-71-1; 5-Fluoro-2-chloromethylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our production of 2-(Chloromethyl)-5-Fluoroimidazo[1,2-A]Pyridine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.