Description

3-Cyano-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic building block, specifically a pyridine boronic ester derivative, designed for advanced synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable intermediates for drug discovery, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its boronic ester functionality for structural diversification.
• Material Science & OLED Development: Serves as a precursor for creating electron-transport materials, ligands for metal-organic frameworks (MOFs), and complex organic semiconductors used in electronic devices.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and diagnostic applications.
• Catalyst & Ligand Design: Utilized as a starting material for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.
• Academic & Contract Research: A critical reagent for methodological development in organic synthesis and for producing custom compounds in contract research organizations (CROs).

Basic Information

Product Name	3-Cyano-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine
CAS No.	878194-92-4
Molecular Formula	C13H15BN2O2
Molecular Weight	242.09 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinecarbonitrile; 3-Cyano-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Pyridinecarbonitrile, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyanopyridine; 3-Cyano-4-pyridinylboronic acid pinacol ester; 4-Pinacolatoboryl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR (1H and 13C), and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH, FDA guidelines for drug master files (DMFs), and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.