Description

8-(5-Nitropyridin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is a high-value, functionalized spirocyclic compound featuring a nitropyridine moiety, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique heterocyclic architecture makes it an essential building block for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides and insecticides, leveraging the bioactive nitropyridine scaffold.
• Ligand and Catalyst Development: Serves as a sophisticated ligand precursor in transition metal catalysis for asymmetric synthesis.
• Material Science: Building block for creating functional organic materials with specific electronic or photophysical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	8-(5-Nitropyridin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane
CAS No.	877790-46-0
Molecular Formula	C14H17N3O4
Molecular Weight	291.30 g/mol
Synonyms	8-(5-Nitropyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(5-nitro-2-pyridinyl)-; 8-(5-Nitro-2-pyridyl)-1,4-dioxa-8-azaspiro[4.5]decane; 2-(1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)-5-nitropyridine; 5-Nitro-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)pyridine; 877790-46-0; 8-(5-Nitropyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Every batch of 8-(5-Nitropyridin-2-Yl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, handling and storage should minimize exposure to direct light or prolonged artificial lighting.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.