Description

6-(Thiophen-3-Yl)-Nicotinic Acid is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines nicotinic acid and thiophene moieties to create a versatile scaffold for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis: Serves as a versatile ligand or core structure for creating metal-organic frameworks (MOFs) and catalysts in organic transformations.
• Material Science: Employed in the research and development of organic semiconductors, conductive polymers, and advanced electronic materials.
• Chemical Biology Probe: Utilized as a molecular scaffold for designing probes to study enzyme function and biological pathways.
• Custom Synthesis: Acts as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	6-(Thiophen-3-Yl)-Nicotinic Acid
CAS No.	877674-90-3
Molecular Formula	C10H7NO2S
Molecular Weight	205.23 g/mol
Synonyms	3-(Thiophen-3-yl)pyridine-5-carboxylic acid; 6-(3-Thienyl)nicotinic acid; 5-Carboxy-3-(3-thienyl)pyridine; Nicotinic acid, 6-(3-thienyl)-; 3-Thiophen-3-yl-pyridine-5-carboxylic acid; 6-(Thiophen-3-yl)pyridine-3-carboxylic acid; 877674-90-3
EINECS	Contact for details

Quality Control

Our 6-(Thiophen-3-Yl)-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.