Description

Methyl 5-(Bromomethyl)Nicotinate is a versatile and high-value brominated nicotinate derivative, serving as a critical building block in advanced organic synthesis. Its primary commercial value lies in its dual functionality, featuring both an ester group and a reactive bromomethyl group, which enables efficient derivatization and incorporation into complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to construct novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for creating advanced pesticides, herbicides, and plant growth regulators with improved efficacy.
• Ligand and Catalyst Development: Used to prepare functionalized pyridine-based ligands for metal catalysis and coordination chemistry.
• Material Science Research: Intermediate in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	Methyl 5-(Bromomethyl)Nicotinate
CAS No.	877624-38-9
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	5-(Bromomethyl)nicotinic acid methyl ester; Methyl 5-(bromomethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-(bromomethyl)-, methyl ester; Nicotinic acid, 5-(bromomethyl)-, methyl ester; 5-Bromomethyl-nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-(Bromomethyl)Nicotinate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.