Description

(3-Hydroxymethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected intermediate of significant importance in modern synthetic chemistry. This compound matters as a versatile building block, enabling the controlled synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key protected precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system and infectious diseases.
• Peptidomimetic Chemistry: Used in the construction of peptide-like molecules where the hydroxymethyl and protected carbamate groups are essential for bioactivity and stability.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, structurally defined intermediates.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development and exploring new chemical spaces.

Basic Information

Product Name	(3-Hydroxymethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	877593-11-8
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	tert-Butyl N-(3-(hydroxymethyl)pyridin-2-yl)carbamate; 2-(((tert-Butoxycarbonyl)amino)methyl)pyridin-3-ol; N-Boc-3-(hydroxymethyl)-2-aminopyridine; Boc-3-(hydroxymethyl)-2-AP; (3-Hydroxymethyl-2-pyridyl)-carbamic acid tert-butyl ester; 2-Amino-3-(hydroxymethyl)pyridine N-Boc derivative; N-(tert-Butoxycarbonyl)-3-(hydroxymethyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our (3-Hydroxymethyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.