Description

tert-Butyl 3-Formyl-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Used in the construction of complex fused heterocyclic systems due to its reactive formyl and protected amine functionalities.
• API Development: Employed in the research and development stages of Active Pharmaceutical Ingredient (API) process chemistry.
• Bioconjugation: The aldehyde group can be utilized for conjugation reactions in the development of antibody-drug conjugates (ADCs) or other bioconjugates.

Basic Information

Item	Detail
Product Name	tert-Butyl 3-Formyl-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate
CAS No.	877260-55-4
Molecular Formula	C13H14N2O3
Molecular Weight	246.26 g/mol
Synonyms	1-Boc-3-formyl-1H-pyrrolo[3,2-c]pyridine; tert-Butyl 3-formylpyrrolo[3,2-c]pyridine-1-carboxylate; 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 3-formyl-, 1,1-dimethylethyl ester; 3-Formyl-1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-1H-pyrrolo[3,2-c]pyridine-3-carboxaldehyde; Boc-3-formyl-7-azaindole
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Formyl-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.