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Azido-Peg10-Alcohol CAS NO 877239-09-3
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CAS No.:877239-09-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Azido-PEG10-alcohol is a heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive azide group and a terminal hydroxyl group. This compound is a crucial building block in bioconjugation and materials science, enabling the facile, site-specific modification of biomolecules and surfaces via click chemistry. It is essential for researchers and manufacturers in the pharmaceutical, diagnostics, and advanced materials sectors who require reliable, high-purity linkers for drug delivery systems, hydrogel formation, and surface functionalization.
Application
- Bioconjugation and Linker Chemistry: Serves as a versatile spacer and linker for attaching drugs, dyes, or targeting ligands to antibodies, proteins, or nanoparticles via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC).
- Drug Delivery Systems: Used to create PEGylated prodrugs or to functionalize liposomes and polymeric micelles, enhancing solubility, stability, and pharmacokinetic profiles.
- Surface Modification and Functionalization: Enables the grafting of bioactive molecules onto materials, polymers, or biosensor surfaces to create biocompatible interfaces.
- Hydrogel and Biomaterial Synthesis: Acts as a cross-linking agent or functional monomer in the development of PEG-based hydrogels for tissue engineering and 3D cell culture.
- Diagnostic Reagent Development: Facilitates the labeling of oligonucleotides, peptides, or other probes for use in assays, imaging, and diagnostic kits.
- Polymer Chemistry: Employed as a macroinitiator or functional chain-transfer agent in the synthesis of block copolymers with tailored properties.
Basic Information
| Product Name | Azido-PEG10-alcohol |
| CAS No. | 877239-09-3 |
| Molecular Formula | C22H45N3O11 |
| Molecular Weight | 527.61 g/mol |
| Synonyms | 1-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-32-ol; 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; Azido-PEG10-OH; N3-PEG10-OH; α-Azido-ω-hydroxy decaethylene glycol; PEG10 Azide Alcohol; Azido-terminated PEG monomethyl ether (HO-PEG10-N3) |
| EINECS | Contact for details |
Quality Control
Our Azido-PEG10-alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting standards for research and commercial use. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow viscous liquid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 1.0% |
| Average Molecular Weight | 520 - 540 g/mol |
| Functional Group Assay (Azide) | ≥ 90% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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