Description

2-Chloro-5-Ethoxy-4-Iodopyridine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. Its unique substitution pattern makes it an essential intermediate for medicinal chemists and process development scientists.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-Chloro-5-Ethoxy-4-Iodopyridine
CAS No.	877133-33-0
Molecular Formula	C7H7ClINO
Molecular Weight	283.49 g/mol
Synonyms	4-Iodo-2-chloro-5-ethoxypyridine; 5-Ethoxy-2-chloro-4-iodopyridine; 2-Chloro-4-iodo-5-ethoxypyridine; Pyridine, 2-chloro-5-ethoxy-4-iodo-; 877133-33-0
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Ethoxy-4-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.