Description

7-Aminomethyl-Spiro[3.5]Nonane is a specialized, high-value spirocyclic amine building block of significant interest in advanced organic synthesis. This compound matters for its unique three-dimensional structure, which provides a rigid scaffold that is highly valuable for modulating the physicochemical and biological properties of target molecules. Pharmaceutical and agrochemical R&D teams need it for the development of novel active ingredients, particularly where conformational restriction is a key design strategy.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its spirocyclic core can enhance metabolic stability and target specificity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials requiring rigid, functionalized monomers.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and tools to study biological systems and protein interactions.

Basic Information

Product Name	7-Aminomethyl-Spiro[3.5]Nonane
CAS No.	877125-98-9
Molecular Formula	C10H19N
Molecular Weight	153.27 g/mol
Synonyms	Spiro[3.5]nonan-7-ylmethanamine; 7-(Aminomethyl)spiro[3.5]nonane; 7-Aminomethylspiro[3.5]nonane; Aminomethylspiro[3.5]nonane; 1-Azaspiro[4.5]decan-8-ylmethanamine (tautomer); Spirocyclic C10 Amine; 7-AMSN
EINECS	Contact for details

Quality Control

Every batch of 7-Aminomethyl-Spiro[3.5]Nonane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.