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tert-Butyl 3-Formyl-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate CAS NO 877060-55-4


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CAS No.:877060-55-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl 3-Formyl-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a formyl-substituted pyrrolopyridine core protected by a tert-butoxycarbonyl (Boc) group. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel small-molecule therapeutics, particularly in oncology and central nervous system (CNS) drug discovery.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted cancer therapies.
  • Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
  • API Development: Serves as a building block in the synthetic route of Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
  • Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and cellular pathways.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name tert-Butyl 3-Formyl-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate
CAS No. 877060-55-4
Molecular Formula C13H14N2O3
Molecular Weight 246.26 g/mol
Synonyms 1-Boc-3-formyl-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 3-formyl-, 1,1-dimethylethyl ester; tert-Butyl 3-formylpyrrolo[3,2-c]pyridine-1-carboxylate; 3-Formyl-1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-formyl-1H-pyrrolo[3,2-c]pyridine; Boc-3-formyl-pyrrolo[3,2-c]pyridine
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Quality Control

Our tert-Butyl 3-Formyl-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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