Description

tert-Butyl 3-Iodo-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is a high-value, heterocyclic building block designed for advanced organic synthesis. This compound is critical for medicinal chemistry research, serving as a versatile intermediate in the development of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted small molecule therapeutics.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization campaigns.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with specific biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Heterocyclic Compound Library Synthesis: A valuable input for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl 3-Iodo-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate
CAS No.	877060-48-5
Molecular Formula	C12H13IN2O2
Molecular Weight	344.15 g/mol
Synonyms	1-Boc-3-iodo-1H-pyrrolo[3,2-c]pyridine; tert-Butyl 3-iodo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate; 3-Iodo-1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester; 1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, 3-iodo-, 1,1-dimethylethyl ester; 877060-48-5; 1-Boc-3-iodopyrrolo[3,2-c]pyridine; Boc-3-iodo-pyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Iodo-1H-Pyrrolo[3,2-C]Pyridine-1-Carboxylate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.