Description

3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Carboxylic Acid is a specialized heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex pharmacologically active molecules, particularly within medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, agrochemicals, and other fine chemicals where its unique bicyclic structure introduces specific conformational and binding properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and pesticides with specific modes of action.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Production: A key intermediate for manufacturing complex, high-value specialty chemicals.

Basic Information

Product Name	3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Carboxylic Acid
CAS No.	876718-04-6
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-3-carboxylic acid; 2,3,4,5-Tetrahydro-1,2'-bipyridine-3-carboxylic acid; 3-Carboxy-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl; 1,2'-Bipyridine-3-carboxylic acid, 1,2,3,4-tetrahydro-; Tetrahydrobipyridinylcarboxylic acid; Bipyridine-3-carboxylic acid derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP and research-grade environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.