Description

2-(4-Methyl-Piperazin-1-Yl)-Isonicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the global pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• API Synthesis: Serves as a core structural component for constructing active pharmaceutical ingredients (APIs) with specific target-binding properties.
• Medicinal Chemistry Research: Used in research and development (R&D) for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation: Potential use in creating antibody-drug conjugates (ADCs) or other targeted drug delivery systems due to its functional groups.
• Chemical Biology Probes: Employed in the development of chemical probes for studying biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CRMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	2-(4-Methyl-Piperazin-1-Yl)-Isonicotinic Acid
CAS No.	876717-56-5
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	2-(4-Methylpiperazin-1-yl)isonicotinic acid; 4-Pyridinecarboxylic acid, 2-(4-methyl-1-piperazinyl)-; 2-(4-Methyl-1-piperazinyl)isonicotinic acid; 2-(4-Methylpiperazin-1-yl)pyridine-4-carboxylic acid; 876717-56-5; 4-Carboxy-2-(4-methylpiperazin-1-yl)pyridine; Isonicotinic acid, 2-(4-methyl-1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Methyl-Piperazin-1-Yl)-Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.