Description

2-(5-Bromo-3-Pyridinyl)-Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core linked to a benzonitrile moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides due to its bioactive heterocyclic structure.
• Material Science Research: Serves as a monomer or ligand precursor in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-(5-Bromo-3-Pyridinyl)-Benzonitrile
CAS No.	876601-23-9
Molecular Formula	C12H7BrN2
Molecular Weight	259.10 g/mol
Synonyms	5-Bromo-3-(2-cyanophenyl)pyridine; 2-(5-Bromo-3-pyridyl)benzonitrile; 3-(2-Cyanophenyl)-5-bromopyridine; 5-Bromo-3-(cyanophenyl)pyridine; Benzonitrile, 2-(5-bromo-3-pyridinyl)-; 876601-23-9
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-3-Pyridinyl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.