Description

3-Iodo-2-Mercapto-5-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines an iodine substituent, a thiol group, and a nitro moiety on a pyridine core, enabling diverse chemical transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand Synthesis: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Functional Material Development: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) or semiconductors.
• Cross-Coupling Reactions: The iodine atom makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes due to its reactive thiol and halogen groups.

Basic Information

Product Name	3-Iodo-2-Mercapto-5-Nitropyridine
CAS No.	876489-82-6
Molecular Formula	C5H3IN2O2S
Molecular Weight	281.06 g/mol
Synonyms	5-Nitro-3-iodopyridine-2-thiol; 2-Mercapto-3-iodo-5-nitropyridine; 3-Iodo-5-nitropyridine-2-thiol; 2(1H)-Pyridinethione, 3-iodo-5-nitro-; 3-Iodo-2-mercapto-5-nitropyridine; 3-Iodo-2-thiol-5-nitropyridine; 5-Nitro-3-iodo-2-pyridinethiol
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Mercapto-5-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.