Description

6-Bromo-3-tert-Butyl-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, heterocyclic organic compound featuring a fused triazolopyridine core structure. This molecule is a critical pharmaceutical intermediate and research chemical used in the development of novel active ingredients. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for its utility in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged heterocyclic scaffold.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents and herbicides.
• Material Science: Potential monomer or precursor for advanced organic electronic materials and ligands in catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic chemistry and cross-coupling reactions.

Basic Information

Product Name	6-Bromo-3-tert-Butyl-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	876372-87-1
Molecular Formula	C10H11BrN4
Molecular Weight	267.13 g/mol
Synonyms	6-Bromo-3-(tert-butyl)-[1,2,4]triazolo[4,3-a]pyridine; 3-tert-Butyl-6-bromo-[1,2,4]triazolo[4,3-a]pyridine; 6-Bromo-3-tert-butyl-1,2,4-triazolo[4,3-a]pyridine; 6-Bromo-3-tert-butyl-[1,2,4]triazolo[4,3-a]pyridine; 876372-87-1; tert-Butyl 6-bromo[1,2,4]triazolo[4,3-a]pyridin-3-yl
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-tert-Butyl-[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.