Description

5-Bromo-4-Chloro-2-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its complex halogenated pyrrolopyridine core makes it a critical intermediate for constructing sophisticated molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists working on kinase inhibitors, targeted cancer therapies, and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile halogen handles for cross-coupling reactions.
• Agrochemical Development: Serves as a precursor for creating new active ingredients with potential herbicidal or pesticidal properties.
• Material Science: Potential monomer or precursor for constructing organic electronic materials and functional polymers.
• Chemical Biology: Used as a probe or tag in biochemical assays and for studying protein-ligand interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules.

Basic Information

Item	Detail
Product Name	5-Bromo-4-Chloro-2-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	876343-87-2
Molecular Formula	C7H3BrClIN2
Molecular Weight	372.38 g/mol
Synonyms	5-Bromo-4-chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-5-bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-chloro-2-iodo-; 876343-87-2; 5-Br-4-Cl-2-I-1H-pyrrolo[2,3-b]pyridine; Multi-halogenated pyrrolopyridine; Halogenated heterocyclic building block
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Chloro-2-Iodo-1H-Pyrrolo[2,3-B]Pyridine is produced and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, NMR, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.