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5-Bromo-4-Chloro-1H-Pyrrolo[2,3-B]Pyridine CAS NO 876343-82-7


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CAS No.:876343-82-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Bromo-4-Chloro-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
  • Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core structure.
  • Material Science: Serves as a building block for creating specialized organic electronic materials and functional polymers.
  • Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation and mechanism studies.
  • Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for method development and exploratory synthesis projects.

Basic Information

Product Name 5-Bromo-4-Chloro-1H-Pyrrolo[2,3-B]Pyridine
CAS No. 876343-82-7
Molecular Formula C7H4BrClN2
Molecular Weight 231.48 g/mol
Synonyms 5-Bromo-4-chloro-7-azaindole; 4-Chloro-5-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-5-bromo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-chloro-; 876343-82-7; 5-Br-4-Cl-7-azaindole
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Quality Control

Our 5-Bromo-4-Chloro-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/IR) Conforms
Assay (HPLC) ≥97.0%
Related Substances (HPLC) Total impurities ≤3.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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